It was no mistake that Jake had been sent to Pandora instead of his twin brother. Neither he nor Neytiri was aware that the eternal soul within Jake's manufactured avatar and physical body had a destiny.
Love as real as an avatar
Eywa: Someone you should know
From where I sat, “Avatar” was all about me. OK, ok! It was about you, too—a story about how we treat each other, our planet, and every living thing on it. To me, “Avatar” was about our relationship with the Allness that is God, or as the Na’vi, the blue striped black folk on the distant moon Pandora called it: Eywa.
Loud Mouth in the Balcony 